This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Herbert E. Kaufman, MD

Arch Ophthalmol. 1970;83(2):131.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

FOR MANY YEARS clinical observations in ophthalmology have indicated that there is some local resistance to repeated infections by bacteria and viruses. Until recently, however, the nature of these local immune phenomena have been obscure.

It has recently been found that there is a unique local secretory antibody system which is relatively independent of circulating antibodies. The common circulating antibodies are the M antibody, a macroglobulin antibody usually occurring shortly after infection and not crossing the placenta, and G antibody, a 7 S antibody which generally is the predominant antibody of -globulin. In addition, however, there is a A antibody and a E antibody, the latter being primarily involved in allergic phenomena. The circulating A antibody (a monomer consisting of two heavy chains and two light chains) does not fix complement, although it can neutralize viruses and lyse bacteria. Most important, this A antibody is produced by plasma cells located . . . [Full Text PDF of this Article]

Author Affiliations
Gainesville, Fla

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?