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  Vol. 75 No. 6, June 1966 TABLE OF CONTENTS
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Dose Relationship of Alpha Chymotrypsin in Production of Glaucoma After Cataract Extraction

RALPH E. KIRSCH, MD

Arch Ophthalmol. 1966;75(6):774-775.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In previous communications1,2 it has been shown that a transient, occasionally severe glaucoma occurred in 72% of eyes in which {alpha}-chymotrypsin was used for enzymatic zonulolysis, while a transient but never severe tension elevation was observed in only 23% of the control group. The clinical characteristics and course of this "enzyme glaucoma" were described and evidence was adduced to support the possibility that this transient glaucoma may be the initiating factor leading to imperfect wound healing after cataract extraction with the enzyme. Acers3,4 has confirmed the occurrence of this glaucoma, noting it in 66% of the eyes operated on by him with the use of {alpha}-chymotrypsin. On the other hand Barraquer5 has denied the existence of this complication. While the number of cases studied by Barraquer was small, it was learned that he used only 0.5 cc of {alpha}-chymotrypsin (1:5,000 dilution), whereas in my own studies 2 . . . [Full Text PDF of this Article]


Author Affiliations

Miami

From the departments of ophthalmology, University of Miami School of Medicine and the Mount Sinai Hospital of Greater Miami.


Footnotes

Submitted for publication Dec 13, 1965.

Reprint requests to 1335 Biscayne Blvd, Miami, Fla 33132.



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