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FREDERICK M. BLANTON, MD; IRVIN P. POLLACK, MD

Arch Ophthalmol. 1966;75(6):763-767.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A variety of substances are now used in treating open angle glaucoma; their comparative effectiveness needs further study. Pilocaprine has long been the standard beginning therapy for the early form of this disease. However, it has a maximum duration of action of only four to six hours, and its use results in poor control of ocular tensions part of the time.^1,2 This is particularly true at night, when eight to ten hours may elapse between doses. Frequent use of drops, as is required with pilocarpine, is considered by many patients as a nuisance and a serious objection. The purpose of the study is to compare the effectiveness of pilocarpine with two long-acting medications: epinephrine and echothiophate iodide.

Epinephrine has been known to be effective in the treatment of glaucoma since the early 1900's, but it never achieved great popularity until it was reintroduced in the middle 1950's. It has . . . [Full Text PDF of this Article]

Author Affiliations
Baltimore

From the Glaucoma Service, Wilmer Institute, The Johns Hopkins University School of Medicine, Baltimore. Dr. Blanton is now at 821 East Broward Blvd, Ft. Lauderdale, Fla.

Footnotes
Submitted for publication Nov 3, 1965.

Reprint requests to The Wilmer Institute, Room B-2, Johns Hopkins Hospital, Baltimore, Md 21205 (Dr. Pollack).

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