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Animal and Clinical Studies

FRANCIS A. L'ESPEREANCE, JR., MD

Arch Ophthalmol. 1965;74(6):752-759.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The introduction of laser photocoagulation to ophthalmology has stimulated interest in the utilization of this technique in the treatment of retinal vascular lesions.^1-4 This report explores the general effects of laser radiation upon the various component parts of the retinal vascular system. The histologic response of the vascular and perivascular tissues will be discussed with regard to the absorption, transmission, and scattering potential of these substances. The effect of the laser beam on retinal microaneurysms, neovascularization, and angiomata has been investigated and will be interpreted from the information gathered from the animal and laboratory studies.

Method

Animal Studies.

—Twenty rabbit eyes and six monkey eyes were used to investigate the histologic effects of laser radiation upon the retinal vasculature. Gray chinchilla rabbits, weighing between 3 and 5 kg, and Indian monkeys, weighing between 6 and 8 kg, were used. The pupils were dilated maximally with phenylephrine hydrochloride 10% (Neo-Synephrine) . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Institute of Ophthalmology, Columbia-Presbyterian Medical Center, New York.

Footnotes
Submitted April 19, 1965.

Read before the Section on Ophthalmology at the 114th Annual Meeting of the AMA, New York City, June 20-24, 1965.

Reprint requests to Institute of Ophthalmology, Columbia-Presbyterian Medical Center, 635 West 165th St, New York, NY 10032.

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