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  Vol. 73 No. 5, May 1965 TABLE OF CONTENTS
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Oguchi's Disease

RONALD E. CARR, MD; PETER GOURAS, MD

Arch Ophthalmol. 1965;73(5):646-656.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

In 1907 Oguchi1 described a form of night blindness associated with a diffuse greyish discoloration of the fundus. Over the next 20 years more than 60 cases were observed, all by Japanese authors. In 1927 Scheerer2 reported the first European cases and since then, 24 patients with this disease have been reported on the continent. Klien,3 in 1939, discussed the first case seen in the United States, and follow-up reports on this patient were subsequently made by Wilder4 and Krill.5

The features which differentiate most cases of this type of nyctalopia from other disorders of congenital stationary night blindness are the appearance of the fundus and the fact that prolonged dark adaptation will lead to a disappearance of the abnormal fundus coloration and normalization of all psychophysical testing parameters. Of note also is the peculiar histologic picture. The presence of an abnormally large number . . . [Full Text PDF of this Article]


Author Affiliations

Bethesda, Md

From the Ophthalmology Branch, National Institute of Neurological Diseases and Blindness, National Institutes of Health, United States Public Health Service, Department of Health, Education and Welfare, Bethesda 34, Maryland.


Footnotes

Submitted for publication Oct 2, 1964.

Reprint requests to Ronald E. Carr, MD, Ophthalmology Branch, National Institutes of Diseases and Blindness, Bethesda, Md 20014.



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