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REGINA FRAYSER, PhD; JOHN B. HICKAM, MD

Arch Ophthalmol. 1965;73(5):640-642.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The regulation of retinal blood flow and vessel size in man is still imperfectly understood. Numerous drugs have been used in an effort to produce vasodilatation and an increase in blood flow to the retina and choroid. Bettman and Fellows¹ have shown in cats that many of the peripheral vasodilator and vasoconstrictor drugs do little to influence the intraocular blood volume. Walsh² has reviewed some of the attempts to evaluate the effect of drugs. Until recently, such studies in the human have been limited to estimations of caliber changes in the retinal vessels. Changes in the size of the resistance vessels cannot be detected with confidence by present techniques because of the small size of the vessels. It is now possible by means of photographic techniques to measure the retinal venous oxygen saturation.³ Such measurements yield an index of flow change provided retinal metabolism is not . . . [Full Text PDF of this Article]

Author Affiliations
Indianapolis

From the Department of Medicine, Indiana University School of Medicine, Indianapolis.

Footnotes
Submitted for publication Oct 29, 1964.

Reprint requests to 1110 Michigan St, Indianapolis, Ind 46207 (Regina Frayser, PhD).

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