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MILDRED C. LEVY, HT (ASCP); THOMAS J. COVATTA, HT (ASCP); CAROL MORRIS, HT (ASCP); HANNELORE H. ASCHNER

Arch Ophthalmol. 1965;73(1):122-123.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

We have recently encountered increasing interest in eye sectioning procedures amongst those who experiment in animals with therapeutic agents, and this report is intended to describe the technique which we have evolved. The description is based chiefly on canine eyes and partly on those of rabbits. The former species is almost invariably employed in the course of subacute tests on most drugs and has also been the subject of two reports on drug-induced blindness.^1,2 The rabbit is chiefly employed for the testing of agents intended to be instilled into the conjunctival sac.

The subsequent ability of the technician to prepare good sections depends on the prior proper enucleation and fixation of the globe. These techniques in animals have recently been described for dogs,^3,4 are identical for rabbits, and hence need not be repeated here; what follows is based on the cited descriptions. We fix, embed, and . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

From the Pathology and Toxicology Section, Smith Kline & French Laboratories.

Footnotes
Submitted for publication June 15, 1964.

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