This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

YOSHITOSHI KUROSE, MD; JOSEPH MICHON, JR., MD; IRVING H. LEOPOLD, MD

Arch Ophthalmol. 1964;72(6):844-849.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Some evidence suggests that uveitis may be related to an autoimmune process.^1-5 Previous reports from this laboratory (Hallett, Wolkowicz, Leopold et al,⁶ 1960; Hallett, Wolkowicz, Leopold, et al, 1962²) have described the presence of a rheumatoid factor in 20% of patients with uveitis, demonstrated by the latex agglutination test and the presence of an autoimmune component in 52% by the autoimmune complement fixation test. From those studies Leopold³ suggested that endogenous uveitis could be propagated if not initiated by an autoimmune response.

Autoimmune diseases have been broadly classified into two categories by Burnet^7,8: "disturbed antigen" diseases and "disturbed tolerance" diseases. The former are ex-emplified by Hashimoto's thyroiditis and the latter by systemic lupus erythematosus (SLE). It has been suggested that autoimmune uveitis may be classified into the category of "disturbed antigen" diseases.⁵

Since the description of the lupus erythematosus cell phenomenon by Hargraves . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

From the Research Department, Wills Eye Hospital.

Footnotes
Submitted for publication April 27, 1964.

This investigation was supported by Public Health Service research grants No. (2B-5076) and No. FR-5510 from the National Institutes of Health, and the Hartford Foundation.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?