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J. PEÑA-CARRILLO, MD; FRANK M. POLACK, MD

Arch Ophthalmol. 1964;72(6):811-816.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Experimental and clinical studies have shown that a normal, functioning endothelium is necessary in order to obtain successful penetrating keratoplasties.^1,2 This is in contrast to the good results obtained with preserved corneas in lamellar grafts^1-3 where the absence of corneal cells does not interfere with its transparency. It has been shown by Schaeffer,⁴ in electron microscope studies, that swelling of mitochondria of endothelial cells of corneas preserved in moist chambers at 4 C appears at 24 hours of storage, and that irreversible structural changes occur only after 96 hours of storage. Electron microscope studies, as well as culture of cells obtained from stored or preserved corneas, made with the purpose of determining the viability of the tissue, in a sense, do not show a true picture of what is happening in the corneal endothelium as a whole because they cannot give a panoramic view of the . . . [Full Text PDF of this Article]

Author Affiliations
New York

Fulbright Fellow from the Medical School of the University of Granada, Spain (Dr. Peña-Carrillo).; From the Department of Ophthalmology and The Corneal Center, Columbia-Presbyterian Medical Center.

Footnotes
Submitted for publication March 31, 1964.

Investigation supported by an NONR, C-266 (71) and in part by research grant B-492 (C-10) from the National Institutes of Neurological Diseases and Blindness of the National Institutes of Health, Public Health Service.

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