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Retinoblastoma Occurring in One of a Pair of Identical Twins
YALE C. KANTER, MD;
JOHN E. HARRIS, PhD, MD
Arch Ophthalmol. 1964;72(6):783-787.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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The recorded incidence of retinoblastoma among twins is exceptionally low, and many of the reports are incomplete. The mean frequency of twinning in United States is 1 in 86 births, with one-fourth to one-third being reported as monozygous. One would expect a higher incidence of retinoblastoma occurring among twins, and in particular identical twins, than the literature reveals. Four pairs of monozygosity and probably four others, in which each of the twins developed retinoblastoma are recorded.1,2 In one of the pairs of monozygosity quoted by François, namely that of Duncan and Maynard, there is no evidence to show that the twins were definitely monozygotic.3 Walker *4 has reported the only occurrence of retinoblastoma in one of a pair of identical twins. Six cases of dizygotic twins are recorded, and in only one pair both twins were affected.2
Table 1 summarizes the recorded cases of twinning and retinoblastoma
. . . [Full Text PDF of this Article]
Author Affiliations
Minneapolis
From the Department of Ophthalmology, University of Minnesota Medical School, University of Minnesota.
Footnotes
Read before the Section on Ophthalmology at the 113th Annual Meeting of the American Medical Association, San Francisco, June 22-24, 1964.
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