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Ocular Toxoplasmosis
MICHAEL J. HOGAN, MD;
SAMUEL J. KIMURA, MD;
G. RICHARD O'CONNOR, MD
Arch Ophthalmol. 1964;72(5):592-600.
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Introduction
Ocular toxoplasmosis is a recognized clinical entity. However, proof of the existence of a toxoplasmic eye infection is difficult to establish because: (1) isolation of this organism is rarely possible except from the enucleated eye, or from aspirated aqueous or subretinal fluid; (2) acute systemic infection preceding or associated with the acute eye disease occurs in less than 1% of cases; and (3) serologic and skin test studies reveal only the presence of antibody and do not indicate activity, except in unusual cases.
The evidence that toxoplasmosis affecting the retina and choroid exists with some frequency is as follows: (1) histologic studies after enucleation of inflamed and glaucomatous eyes have revealed this parasite in a considerable number of instances; (2) isolations of Toxoplasma have been made from enucleated eyes in a few instances, and from aqueous and subretinal fluid in rare cases; (3) concomitant systemic and eye involvement with
. . . [Full Text PDF of this Article]
Author Affiliations
San Francisco
From the Francis I. Proctor Foundation and the Department of Ophthalmology, University of California School of Medicine.
Footnotes
Read before the Section on Ophthalmology, at the 113th Annual Meeting of the American Medical Association, San Francisco, June, 1964.
This work was supported in part by research grants NB-0786, NB-00044, NB-01099, National Institute of Neurological Diseases and Blindness, National Institutes of Health, Bethesda, Md.
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