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The Characteristics of Experimental Laser Coagulations of the Retina
KIMIHARU S. NOYORI, MD;
CHARLES J. CAMPBELL, MD;
CATHERINE RITTLER, AB;
CHARLES J. KOESTER, PhD
Arch Ophthalmol. 1964;72(2):254-263.
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Introduction
The technique of laser photocoagulation offers great therapeutic promise to the clinician. In this laboratory a program is under way to evaluate the ocular effects produced by lasers. An important aspect of this study is the documentation of the histologic characteristics of lesions produced by laser photocoagulation. This report defines and illustrates the microscopic appearance of laser coagulations and relates these findings to the clinical appearance of the lesions as observed by ophthalmoscopy. The more familiar xenon arc coagulations are compared to those obtained with the laser.
Previous Reports
The microscopic characteristics of retinal coagulations produced by the xenon arc photocoagulator have been described.1-3 The investigation by Okun particularly related the histologic appearance of the lesion to the intensity of the treatment. In mild lesions there was coagulation necrosis of all retinal layers one hour after treatment. The most marked effect was in the outer layers where hydropic
. . . [Full Text PDF of this Article]
Author Affiliations
New York; Southbridge, Mass
Knapp Memorial Laboratory of Physiological Optics, Institute of Ophthalmology of Presbyterian Hospital, College of Physicians and Surgeons of Columbia University, New York (Drs. Noyori and Campbell, Miss Rittler); Research Division, American Optical Company, Southbridge (Dr. Koester).
Footnotes
Submitted for publication Feb 24, 1964.
This research was supported in part by grant B879 from the National Institute of Neurological Diseases and Blindness, United States Public Health Service.
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