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JACK E. GOLDSTEIN, MD; DAVID G. COGAN, MD

Arch Ophthalmol. 1964;72(2):168-170.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In most instances of optic neuropathy associated with multiple sclerosis it is difficult to ascribe the onset of visual symptoms to a particular precipitating factor. However, some patients with multiple sclerosis have an optic neuropathy that is initially provoked or temporarily aggravated by physical exertion (Uhthoff's symptom¹). It is the purpose of this paper to report four cases of multiple sclerosis with optic neuropathy in which episodes of visual impairment occurred during periods of exercise.

Report of Cases

CASE 1.

—A 25-year-old female was admitted to the Massachusetts General Hospital for evaluation of recurrent episodes of visual impairment that had started four years previously. Initially she had experienced numbness of her right lower extremity which lasted for four weeks. Shortly thereafter the vision in her left eye became limited to identification of large objects but returned to normal in about a month. Immediately after the birth of her child, . . . [Full Text PDF of this Article]

Author Affiliations
Boston

Howe Laboratory of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary.

Footnotes
Submitted for publication Jan 14, 1964.

This work was supported in part by a special fellowship (1 Flo NB 1182-01) from the National Institute of Neurological Diseases and Blindness, United States Public Health Service.

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