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III. Changes in Visual Function and Pupil Size During Topical Dexamethasone Application

MANSOUR F. ARMALY, MD

Arch Ophthalmol. 1964;71(5):636-644.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The clinical significance of the ocular hypertension induced by topical steroid application is ultimately dependent upon the nature and magnitude of its effect on visual function. It has been shown in preceding publications that the effect of dexamethasone on aqueous humor dynamics was reversible in nature^1,2; complete recovery of the pretreatment values of intraocular pressure and outflow facility was achieved one to two weeks after the cessation of dexamethasone application in all the cases studied. It should be pointed out, in this respect, that the duration of dexamethasone application in these studies did not exceed, in general, four to five weeks. The possibility that longer duration of drug application and of hypertension might result in a permanent change in outflow facility has not been definitively ruled out.

The relationship between intraocular pressure level and visual field damage is not a simple one. The involved variables and their relative contribution . . . [Full Text PDF of this Article]

Author Affiliations
lowa City

From the Department of Ophthalmology, State University of Iowa, and the University Hospitals.

Footnotes
Submitted for publication Oct 21, 1963.

This investigation was supported in part by research grant NB-02423 and grant NB-03636 from the National Institute of Neurological Diseases and Blindness, United States Public Health Service, Bethesda, Md.

Dexamethasone 21-phosphate (Decadron phosphate), Merck Sharp & Dohme.

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