This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (14)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Part II

STEVEN PODOS, MD; SUMNER LIEBMAN, MD; ABRAHAM POLLEN, MD

Arch Ophthalmol. 1964;71(4):537-541.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a prior publication,¹ the authors, utilizing total hyphemas produced in rabbits, demonstrated the effects of streptokinase (Kinalysin) and fibrinolysin (Thrombolysin)* in the resolution of these clots, as compared with untreated and saline irrigated controls. Fibrinolysin is a combination of profibrinolysin (plasminogen) and an activator, streptokinase. Both enzyme preparations promoted resolution of fibrin and corneal edema. Red cell debris, however, was unaffected. Irrigation rather than injection of enzyme was necessary for any substantial benefit.

These results have been confirmed by Scheie et al,² who found that continuous 30 minute irrigation with fibrinolysin resulted in the clearing of human blood hyphemas in rabbit eyes. Simple injection was ineffectual. Saline irrigation resulted in poor clearing of clot. In addition, Scheie treated traumatic total hyphemas that were six hours to seven days old in human patients. Glaucoma was present. Results were favorable in all including reirrigation in one patient after he . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis; Boston

From the Massachusetts Eye and Ear Infirmary, and the Harvard Medical School.

Footnotes
Submitted for publication Oct 3, 1963.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?