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R. LEVENE, MD; J. BAUM, MD

Arch Ophthalmol. 1963;70(2):242-249.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Vascularization is a fundamental process that occurs normally during tissue growth and abnormally after tissue injury. In the eye, abnormal new vessel formation is an important clinical problem and has received considerable attention. The cornea is an excellent site for the study of new vessel growth by virtue of its normal avascularity and surface location. Neovascularization of the cornea has been reviewed by Ashton¹ and Cogan.²

During an investigation of experimental glaucoma in the rabbit, produced by an encircling equatorial rubber band, Flocks et al³ noted a circumferential growth of new vessels limited to the peripheral cornea. No direct corneal injury was required. This useful experimental method of producing neovascularization has been used in this study for the further investigation of new vessel growth.

Method

We used adult albino rabbits weighing from 2.5 to 3.0 kg, with normal globes. After a preliminary Schiøtz tonometry on the . . . [Full Text PDF of this Article]

Author Affiliations
New York

Department of Ophthalmology, New York University-Bellevue Medical Center.

Footnotes
Submitted for publication Dec 21, 1962.

These studies were supported by Research Grantsin-Aid B-1951 and NB04230 from the National Institute of Health, Public Health Service, US Department of Health, Education and Welfare.

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