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I. Effect of Physostigmine and of Pilocarpine on Pupillary Movements in Normal Man

IRENE E. LOEWENFELD, PhD

Arch Ophthalmol. 1963;70(1):42-51.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The literature concerning the influence of drugs upon the iris, too voluminous to be presented here, can be grouped roughly into four categories, namely: (1) reports that dealt with the discovery and description of drugs or poisons, in which the pupillary effects were part of the general clinical findings; (2) investigations designed to reveal the mode of action of various drugs; (3) experiments in which drugs of known action were used to clarify the mechanism of physiological phenomena directly or indirectly related to pupillary movements; and (4) description and evaluation of drugs used in ophthalmology for the specific purpose of dilating or contracting the pupil.

In spite of the great popularity which the iris has enjoyed as an indicator in pharmacological experiments, the number of investigations in which the pupillary movements were registered accurately is relatively small. This fact and the great variations in drug responses between species, among individuals, . . . [Full Text PDF of this Article]

Author Affiliations
New York

Department of Ophthalmology, Laboratory of Pupillography, Columbia University, College of Physicians and Surgeons, and the Presbyterian Hospital.

Footnotes
Submitted for publication Oct 31, 1962.

This work was supported by the Harriman Fund and by a grant from the US Public Health Service (Sens. Dis. B-253).

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