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Experimental Aqueous Perfusion in Enucleated Human Eyes
W. MORTON GRANT, MD
Arch Ophthalmol. 1963;69(6):783-801.
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Aqueous perfusion is a convenient and direct means for quantitative evaluation of facility of aqueous outflow (C) in enucleated eyes. The C value is obtained by simple calculation from the rate of injection (F) of saline solution and from the steady state pressure (P) induced in the eye. (Under steady state conditions of equal rate of flow in and out, the relationship at moderate pressures can be expressed as F/P = C.) This is the common basis for evaluation of C by several procedures which differ only in technical details of measurement of flow rate and pressure. (More complex considerations are involved when aqueous perfusion of the eye is applied in vivo or in study of elastic properties of the eye. These are beyond the scope of the present article.)
In study of the mechanics of the outflow channels, good use has been made of aqueous perfusion. Applied to animal eyes,
. . . [Full Text PDF of this Article]
Author Affiliations
Boston
From the Howe Laboratory of Ophthalmology, Massachusetts Eye and Ear Infirmary, and Harvard University Medical School.
Footnotes
Submitted for publication Sept. 18, 1962.
This work was supported by grants from the Alfred P. Sloan Foundation and from the Institute of Neurological Diseases and Blindness of the National Institutes of Health, United States Public Health Service (Research Grant B-218), and by the Concordia Foundation.
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