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Central Scotomata Due to Chlorpropamide (Diabenese)Case Report
CRAIG W. GEORGE, MD
Arch Ophthalmol. 1963;69(6):773.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Bilateral central scotomata may occur as an unusual toxic reaction related to the use of chlorpropamide (Diabenese *) as an oral hypoglycemic agent. The patient in this report developed blurred vision two days after beginning to take chlorpropamide. Givner1 has reported a patient who developed bilateral central scotomata after six months of chlorpropamide therapy.
One must be constantly aware of the toxic aspect of any medication. Givner points out that one might be inclined to ascribe visual loss only to retinopathy in the diabetic patient.
Report of Case
A 53-year-old railroad worker was seen by his family physician on March 3, 1962, in a routine examination for fatigue and weakness. Examination was normal except for glycosuria 3+. Fasting blood sugar was 343 mg%. Complete blood count was normal. On March 10, 1962, the patient began to take chlorpropamide 250 mg each morning. Diabetic diet was advised. Two days later, the
. . . [Full Text PDF of this Article]
Author Affiliations
Alliance, Ohio
Footnotes
Submitted for publication Nov 29, 1962.
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