This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (21)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

CAPT. M. K. JACK, MC; R. W. SORENSON, MD

Arch Ophthalmol. 1963;69(6):730-732.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Vaccination against smallpox with a live attenuated virus has resulted in a variety of statistically minor but clinically unusual complications including reported cases of encephalitis, acute renal failure, glomerulonephritis, thrombocytopenic purpura, and vaccinial keratitis.¹ The keratitis is considered a serious ocular complication² in spite of reports which allude to its benignity when treated with a number of therapeutic agents including cortisone.³

Presented here is a single case of keratitis immediately associated with generalized vaccinia, thought to clinically represent vaccinial keratitis which was treated with 5-iodo-2'-deoxyuridine (IDU).*

Realizing that a single case might stand as apocryphal concerning the efficacy of treatment, we still feel that the unusual circumstances of the corneal disease and the course of the illness after IDU treatment are of significant interest.

Vaccinia is a laboratory virus evolved from cowpox or variola virus which is modified by animal passage through calves or rabbits and irreversibly . . . [Full Text PDF of this Article]

Author Affiliations
USA; Phoenixville, Pa

Present address: 4314 W. Slauson Blvd., Los Angeles 43, (Dr. Sorenson).

Footnotes
Submitted for publication Oct. 19, 1962.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?