This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

H. PARISIER, M.D.; A. B. HOUSSAY, M.D.; A. GOMEZ MORALES, M.D.; A. FERRER ARATA, M.D.; J. CORDERO FUNES, Ph.D.; N. ALTSCHÜLER, Ph.D.

Arch Ophthalmol. 1963;69(4):479-483.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Graves' disease is generally associated with a typical ophthalmopathy. The occurrence and intensity of this ophthalmopathy are not related to the course of hyperthyroidism. Pituitary ophthalmotropic factors, other than thyrotropic hormone, are considered to be the cause of the exophthalmos.³

Two principal clinical types of exophthalmopathy have been described, namely, the simple and the malignant exophthalmos; however, most of the patients show a mixed picture, presenting some characteristics of each one. In severe exophthalmos, underlying edema and cellular infiltration of the conjunctiva and structures about the eye are clinically obvious.

There have been many hypotheses on the mechanism of the ophthalmopathy of Graves' disease. It is now generally accepted that the proptosis is due to an increased volume of the retrobulbar tissues of the eye.^3,9 Several factors may play a part in the filling of the orbit: an increase in retrobulbar fat,^5,9 an increase in the size . . . [Full Text PDF of this Article]

Author Affiliations
Buenos Aires, Argentina

Centro de Endocrinología, Ministerio de Asistencia Social y Salud Pública, Godoy Cruz 1221, Buenos Aires, Argentina.

Footnotes
Submitted for publication June 26, 1962.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?