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PAUL A. CIBIS, M.D.; BERNARD BECKER, M.D.; EDWARD OKUN, M.D.; SAMUEL CANAAN, M.D.

Arch Ophthalmol. 1962;68(5):590-599.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

Silicone rubber has been widely used as implant material in plastic surgery and in retinal detachment procedures.¹ Liquid silicone was first injected into the vitreous cavity of rabbits by Stone,² who reported that silicone fluids of various viscosities were well tolerated and produced "very little change in the rabbit eyes over a period of two years." He went on to predict that it might be possible to find a "viscosity" that would maintain the "clarity" of the vitreous and help in "replacing the retina." Recently, other investigators^3-5 have confirmed Stone's observations. However, their animal experiments emphasized the possibilities of complications. Everett⁴ reported cataract formation following the injection of liquid silicone into the vitreous cavity of rabbits; Galavin⁵ produced glaucoma by the injection of liquid silicone into the posterior chamber of the rabbit eye.

The present study serves a dual purpose: (1) to report further . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine.

Footnotes
Submitted for publication April 23, 1962.

Read before the Section on Ophthalmology, 111th Annual Meeting of the American Medical Association, Chicago, June 26, 1962.

This investigation was supported in part by research grant B-1789 from the National Institute of Neurological Diseases and Blindness, National Institutes of Health, Public Health Service.

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