This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (54)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Assessment of Value and Basis

G. B. ARDEN, M.B.B.S., B.Sc., Ph.D.; M. R. FOJAS, M.D.

Arch Ophthalmol. 1962;68(3):369-389.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In primary pigmentary retinal degeneration (retinitis pigmentosa) the electroretinogram (ERG) has been reported to be extinguished (Karpe, 1945; Björk and Karpe, 1951; Armington, 1954; François, 1952; Dodt and Wadensten, 1954). The ERG as used by Karpe and his followers is purely a measure of rod function, and in these first investigations the highly specific depression of the ERG (especially of the b-wave) was thought to confirm the theory that the disease was a primary degeneration of the rods. However, some discrepancies soon became apparent. Dodt and Wadensten (1954) and Riggs (1954) commented that in patients with well-preserved vision no electrical response could be recorded at all, even though the light intensities and conditions of the test were such that the photopic system of the retina was active. Riggs suggested that functional "perforations" occurred in the retinal periphery, which acted as electrical shunts and prevented the remote corneal electrode picking up . . . [Full Text PDF of this Article]

Author Affiliations
London

Present address: University of the Philippines, College of Medicine, Manila (Dr. Fojas).; Ophthalmological Research Unit (Medical Research Council), Institute of Ophthalmology, Judd St., London.

Footnotes
Submitted for publication Nov. 6, 1961.

In receipt of a Traveling Fellowship from the Colombo Plan (Dr. Fojas).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?