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DAVID O. JESBERG, M.D.

Arch Ophthalmol. 1962;68(3):331-336.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

This paper reports a series of observations made during the past 2 years in patients with aniridia. This condition is familial, and the transmission is dominant by an autosomal gene. It demonstrates high penetrance and variable expression. Visual acuity was less than 20/100 in 86% of aniridic eyes, as tabulated from the literature^1,2 plus my own few cases (Fig. 1). Aniridia, therefore, represents an important medical and surgical problem to the ophthalmologist and a social challenge to the community.

Aniridia is characterized by reduction of the iris, and in the complete case the iris rudiment is visible only when the anterior chamber angle is examined with slit lamp or gonioscope. In modified cases the iris may be regionally deficient. Associated with the iris defects are persistence of pupillary membrane and of the tunica vasculosa lentis. Cataract and displacement of the lens may . . . [Full Text PDF of this Article]

Author Affiliations
San Francisco

Clinical Instructor of Ophthalmology, University of California Department of Ophthalmology and Junior Research Ophthalmologist, Francis I. Proctor Foundation for Research in Ophthalmology. Chief of Ophthalmology, United States Veterans Administration Hospital, Fort Miley.; From the Francis I. Proctor Foundation for Research in Ophthalmology, University of California San Francisco Medical Center, San Francisco 22. This work was supported by Grant B-3292 from the National Institutes of Health.

Footnotes
Submitted for publication Feb. 23, 1962.

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