This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

J. STEVENS ANDREWS, Ph.D.

Arch Ophthalmol. 1962;68(2):264-266.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A recent report¹ on the pathology and histochemistry of arcus senilis emphasized the lipid nature of the corneal deposits and suggested that an understanding of arcus formation might explain some of the factors involved in fat deposition in other nonadipose tissues of the body.

Although these investigators identified the components of arcus as probably a cholesterol derivative with some associated phospholipid and glyceride, the values obtained were necessarily only semiquantitative, and the presence of abnormal quantities of the minor components remains equivocal. Indeed, the lack of a definitive histochemical test for glyceride suggests the possibility that this class of compounds may not contribute, even in a minor fashion, to the observed arcus.

The purpose of this investigation was to identify by means of biochemical procedures the principal lipid components of arcus senilis and to establish the quantities of these materials present in the cornea and the sclera.

Methods and . . . [Full Text PDF of this Article]

Author Affiliations
Boston

Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary, 243 Charles St.

Footnotes
Submitted for publication March 12, 1962.

This investigation was supported by a PHS research grant No. H-4051 from the National Heart Institute, Public Health Service.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?