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DANIEL TOUSSAINT, M.D.; DAVID G. COGAN, M.D.; TOICHIRO KUWABARA, M.D.

Arch Ophthalmol. 1962;67(1):42-47.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A previous report from this laboratory concerned the histologic abnormalities in the vessels of diabetic retinopathy.¹ The present report is concerned with the extravascular changes. These extravascular lesions of diabetic retinopathy consist of hemorrhages and a miscellany of hyalinelipid material that both clinicians and pathologists have called exudate. The implication has been that the vessels have become leaky as a result of arteriolar obstruction or pathologic changes in the vessel walls and that the extravascular material is serum or material derived from serum.

It was the purpose of the present study to document the histopathologic changes on the basis of material at our disposal, to reassess the evidence of an exudative basis for the accumulation of abnormal material in the retina, and to correlate the occurrence of these deposits with the vascular changes. The subject of hemorrhages has been omitted from this discussion since it has been abundantly described . . . [Full Text PDF of this Article]

Author Affiliations
Boston

NATO Fellow (Dr. Toussaint).; Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary.

Footnotes
Submitted for publication July 12, 1961.

This investigation was supported by a U.S. Public Health Service Research Grant No. H-4051 from the National Heart Institute, Public Health Service, and a gift for Studies Pertinent to the Ocular Effects of Diabetes.

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