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  Vol. 66 No. 5, November 1961 TABLE OF CONTENTS
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Effect of Polymyxin B Sulfate on Pseudomonas Corneal Ulcers

J. WALLACE McMEEL, M.D.; RONALD M. WOOD, Ph.D.; LAWRENCE B. SENTERFIT, Sc.D.

Arch Ophthalmol. 1961;66(5):646-648.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Treatment of Pseudomonas corneal ulcers has been disappointing with encouraging results appearing in the literature only within the past 5 years. Morelli's1 review of the literature up to 1922 shows a story of almost unanimous failure, with 23 enucleations, 14 leukomas, and 1 nebula. Moorman's2 review of 24 cases from 1922 until 1939 showed 12 eyes enucleated, 9 with vision 20/200 or less, and only 3 with vision better that 20/200; whereas 25 cases from 1939 until 1955 treated with sulfa compounds or antibiotics other than polymyxin B sulfate resulted in 10 enucleations, 9 eyes with 20/200 vision or less, and 6 eyes with vision better that 20/200. Of 11 cases treated by Moorman with polymyxin B or E sulfate. one eye was enucleated, 7 had vision 20/200 or less, and 3 had vision better than 20/200. There were 8 cases of corneal ulcer due to Pseudomonas reported . . . [Full Text PDF of this Article]


Author Affiliations

Baltimore

From the Wilmer Ophthalmological Institute of The Johns Hopkins University and Hospital.


Footnotes

Submitted for publication May 25, 1961.

This work was supported, in part, by Grant B-43, U.S. Public Health Service.



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