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Ocular Involvement in Leukemia and Allied Disorders
RAYMOND A. ALLEN, M.D.;
BRADLEY R. STRAATSMA, M.D.
Arch Ophthalmol. 1961;66(4):490-508.
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It has long been known that the eye is often involved in leukemia and allied disorders. In some reported series clinical observations have been corroborated by biopsy, generally of lids or conjunctiva, and less commonly the globe has been examined. By and large, the exact nature, the extent, and the sites of involvement of the eye by the various reticuloendothelial neoplastic processes remain to be defined.
Intraocular leukemic disease has been noted as a discrete tumor mass by Wiener,1 McGavic,2,3 Reese,4 and others; specific consideration has been given to fundus changes associated with leukemia by Borgeson and Wagener,5 Goldstein and Wexler,6 Gibson,7 and Dawson.8 Involvement of the orbit and adnexa has been well documented,2,3,9-11 and conjunctival disease has been recorded in many detailed reports.12,13,14-16
Within the past 2 years we have had the opportunity to examine the globes of 76 patients
. . . [Full Text PDF of this Article]
Author Affiliations
Los Angeles
From the Department of Pathology and the Division of Ophthalmology, Department of Surgery, University of California Medical Center, Los Angeles 24.
Footnotes
Submitted for publication May 17, 1961.
Read before the Section on Ophthalmology at the 110th Annual Meeting of the American Medical Association, New York, June 25-30, 1961.
The study was supported by Research Grant B-2866, from the National Institute of Neurological Diseases and Blindness, and by Research Grant G-237, from the National Council to Combat Blindness, Inc.
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