This Article  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Sidney Lerman, M.D.
University of Rochester Medical School 260 Crittenden Blvd. Rochester 20, N.Y.

Arch Ophthalmol. 1961;66(3):448-449.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor:

—In reply to Dr. Kinoshita's comments on my recent article ("Carbohydrate Metabolism in the Rat Lens as Related to the Age of the Animal," ARCH. OPHTHAL. 65:181, 1961), I would certainly agree with him that the TPNH/TPN ratio does not necessarily reflect the activity of the hexose monophosphate shunt. However, what I had intended to indicate was that this ratio taken in context with the C₁C₆ ratio and an active G-6-P dehydrogenase system might indicate the presence of an active shunt pathway in the young rat lens. As Dr. Kinoshita has pointed out, the presence of relatively large amounts of total TPN in this organ is also a significant indicator for the presence of such a pathway of glucose oxidation.

With respect to Dr. Kinoshita's comment regarding the drop in C-1 oxidation of glucose with age, he states that this is not surprising since . . . [Full Text PDF of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?