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J. REIMER WOLTER, M.D.

Arch Ophthalmol. 1961;65(6):847-854.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Saccular dilations arising from one side of the retinal capillaries are part of the typical pathology of diabetic retinopathy and are known as capillary microaneurysms. They were first described by Nettleship¹ in 1888. However, it seems that little attention was paid to Nettleship's discovery and capillary microaneurysms were rediscovered by Ballantyne and Loewenstein² in 1944. This rediscovery resulted in great interest and an extensive number of papers concerning the structure, development, and significance of the microaneurysms in diabetic retinopathy. Outstanding are those of Ballantyne,^3,4 Friedenwald,^5-7 Ashton,^8-12 and Pope.¹³

Several theories have been suggested to explain the development of diabetic retinal microaneurysms. Ballantyne^3,4 considered a combination of stasis and increase of venous pressure caused by thrombosis of smaller retinal veins and additional local weakening of the capillary wall caused by endothelial degeneration as responsible for the saccular dilation. He observed the deposition of fat . . . [Full Text PDF of this Article]

Author Affiliations
Ann Arbor, Mich.

From the Department of Ophthalmic Surgery, University of Michigan Medical Center.

Footnotes
Submitted for publication Feb. 17, 1961.

Supported by Grant No. B-2873 of the U.S. Department of Health, Education, and Welfare.

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