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BERNARD BECKER, M.D.

Arch Ophthalmol. 1961;65(6):832-836.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Recently a transport system for iodide which resembles the thiouracil-treated thyroid gland has been demonstrated in the rabbit eye. Iodide was accumulated in ciliary body-iris preparations in vitro and was transported out of the rabbit eye in vivo.¹ Saturation by iodide and inhibition by perchlorate, fluoroborate, and related ions characterized the accumulation as well as the transport system. The transport of iodide out of the vitreous humor of the rabbit eye might account for the deficit of this ion in the aqueous humor as compared with plasma concentrations.^2,3 The purpose of the present study was to evaluate the turnover of systemically administered I¹³¹ in the rabbit eye with an intact iodide transport system and in the animal subjected to perchlorate inhibition.

Methods

Unanesthetized 2-3 kg. male albino rabbits were used throughout. Nonlabeled sodium iodide in doses of 3µM/kg. was administered intraperitoneally to all animals in order to . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Department of Ophthalmology and the Oscar Johnson Institute, Washington University School of Medicine, St. Louis.

Footnotes
Submitted for publication March 17, 1961.

This investigation was supported in part by a research grant, B-621, from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, U.S. Public Health Service.

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