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EDWARD TAMLER, M.D.; ROLF EISSLER, M.D.

Arch Ophthalmol. 1961;65(4):514-516.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although the intracranial and optic nerve pathology in Schilder's disease is well known, the writers have been able to find only a rare report of its intraocular pathology.^1,2 It is the purpose of this paper to report the intraocular pathology in a proven case of this disease.

Schilder's disease, also known as encephalitis periaxialis, or progressive degenerative subcortical encephalopathy, is one of the demyelinating diseases affecting the white matter of the cerebral hemispheres. It is characterized by spastic paralysis, mental deterioration, blindness, deafness, and eventually death. It is most often seen in infants and young children. The course may be acute, subacute, or chronic. The development of the signs mentioned above depends on which area of the brain is affected. In children epileptiform seizures are also seen. Blindness usually occurs late in the disease and a majority of the patients go on to partial or complete blindness. Optic nerve . . . [Full Text PDF of this Article]

Author Affiliations
San Francisco

From the Division of Ophthalmology, Department of Surgery, Stanford University School of Medicine, Palo Alto, Calif., and the Presbyterian Hospital and Medical Center, San Francisco.

Footnotes
Submitted for publication Aug. 8, 1960.

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