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Centrocecal Scotomata as the Presenting Sign in Pernicious Anemia
SIDNEY LERMAN, M.D.;
ALEXANDER L. FELDMAHN, M.D.
Arch Ophthalmol. 1961;65(3):381-385.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Progressive visual impairment resulting in optic atrophy is not a common finding in patients with pernicious anemia and subacute degeneration of the spinal cord. In 1959, Hamilton, Ellis, and Sheets1 in a comprehensive review of the literature found only 28 well-documented cases of optic neuropathy associated with pernicious anemia and added 1 case of their own. The onset of visual impairment antedated other manifestations of pernicious anemia in 9 of the reported cases, while the ocular involvement was the only significant finding in 3 cases. In view of the relative scarcity of reports on visual field defects as a manifestation of impaired absorption of B12, the following case is presented.
Report of Case
The patient is a 57-year-old white man who was first seen in October, 1959, with the complaint of slow progressive failure of vision over the preceding 6 months. He had been referred by an optometrist
. . . [Full Text PDF of this Article]
Author Affiliations
Rochester, N.Y.
From the Department of Surgery, Division of Ophthalmology and the Department of Medicine (Neurology) of the University of Rochester School of Medicine and Dentistry.
Footnotes
Submitted for publication Sept. 7, 1960.
This work was supported by research funds granted by the Rochester Eye Bank and Research Society, Inc.
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