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JUN TSUTSUI, M.D.; SAEKO WATANABE, B.Sc.

Arch Ophthalmol. 1961;65(3):375-380.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1914, Friedberg¹ observed a virulent inflammation in the host tissue surrounding an implant 14 days postoperatively and inferred from this observation that the serological relationship played a role in graft healing. The inflammation, which was rapidly reduced, was tentatively interpreted as an anaphylactic reaction. Following this report, and especially recently, many authors, such as Müller and Maumenee,^2-4 Choyce⁵ Babel and Bourquin,⁶ Maumenee,⁷ Morawiecki,⁸ Basu and Ormsby,^9,10 Kornblueth,¹¹ Lieb and Lerman,¹² Kamata,¹³ and Arai,^14,15 have recognized an antigen-antibody reaction after homo- and heterocorneal grafting.

Postoperative graft opacity—the most unhappy complication of keratoplasty for the surgeon as well as the patient—may have a variety of causes. In 1948, Paufique, Sourdille, and Offretin¹⁶ applied the term "maladie du greffon" to the opacity that arose inexplicably without manifest operative complications. Local allergy was regarded as one of the most important causal factors, . . . [Full Text PDF of this Article]

Author Affiliations
Okayama-Shi, Japan

From the Eye Department and Eye Bank Laboratory, Okayama Rosai Hospital.

Footnotes
Submitted for publication Sept. 19, 1960.

This work was supported by a Grant-in-Aid from the Arnold Reuben Fight for Sight Fund of the National Council to Combat Blindness, Inc., New York City.

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