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TSUYOSHI YAMASHITA, M.D.; PAUL CIBIS, M.D.

Arch Ophthalmol. 1961;65(1):49-58.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

In 1931, Chuta Oguchi¹ produced experimental retinitis proliferans in the eyes of rabbits by intravitreal injection of autogenous blood. Ashton² recently succeeded in producing vascular proliferation into the vitreous body of kittens by raising them in a chamber containing highly oxygenated air. In this study, we induced fibrous and vascular tissue proliferation into the vitreous of rabbits by injecting autogenous blood or saccharated iron oxide.

Materials and Methods

One-tenth of a milliliter of blood was withdrawn from the ear artery of 18 rabbits and injected into the vitreous of the same animal. The right eyes were used for the experiment whereas left eyes were injected with saline or sucrose solution for control. After 2 weeks to 1 year clinical observation, the animals were killed and the eyes were enucleated, fixed in formalin solution, and embedded in paraffin. The sections were stained with Prussian blue^3,4 and counter-stained . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

From the Department of Ophthalmology and the Oscar Johnson Institute, Washington University, School of Medicine.

Footnotes
Submitted for publication Aug. 29, 1960.

This research was supported in part by a grant (No. B-1789) from the National Institute of Neurological Diseases and Blindness of the National Institutes of Health, Public Health Service.

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