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In Vitro Membrane Potential of the Cat Ciliary Body
MONTE G. HOLLAND, M.D.;
DALLAS MALLERICH;
JOSEPH BELLESTRI, B.S.;
BRUCE TISCHLER, B.S.
Arch Ophthalmol. 1960;64(5):693-696.
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Introduction
The problem of whether a potential exists across the epithelium of the ciliary body, the presumed site of aqueous humor formation, is of considerable theoretical interest. If such a potential exists it evidently will influence the steady state distribution of ions between the blood and aqueous humor and thus must be considered in any analysis of aqueous humor dynamics.1
This potential would be of further interest because, at least in the frog skin, it is believed to be due to the active transport of sodium ion,2 and there is evidence that the active transport of sodium ion plays an important role in aqueous humor formation.3
It is the purpose of this communication to report the measurement of a bioelectric potential generated by the ciliary body of the cat, experimentally prepared as an isolated membrane between two reservoirs.
A. Materials and Methods
Adults cats of both sexes were
. . . [Full Text PDF of this Article]
Author Affiliations
New Orleans
From the Department of Ophthalmology, Tulane University School of Medicine.
Footnotes
Submitted for publication June 10, 1960.
This investigation was supported in part by research grant 21936, and research grant B-2212, from the National Institutes of Health, Public Health Service.
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