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S. M. DRANCE, M.B., F.R.C.S. (Eng.); V. R. WOODFORD, Ph.D.; F. Carr, B.Sc., F.B.O.A. (Hons.); N. Leegwater

Arch Ophthalmol. 1960;64(5):668-670.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1956 a report by E. liuma¹ et al. concerning the use of anthranilic acid in simple glaucoma appeared in the Japanese literature. The authors used 0.2 to 0.6 mg/kg. of body weight daily and detected lowering of the intraocular pressure, a decrease in phasic tension variation, and a recovery of visual field in 7 patients with chronic simple glaucoma. The authors claimed that with long-term administration the visual fields in 8 glaucomatous patients recovered. In 1958, Yasuda² studied the mechanism of the fall in intraocular pressure induced by anthranilic acid in rabbits. He also stated as a result of his investigations that there was a definite decrease of aqueous flow and of the total CO₂ and bicarbonate ion concentration of aqueous. In 1959, Fitterman and Simpson³ presented a preliminary report of amino . . . [Full Text PDF of this Article]

Author Affiliations
Saskatoon, Sask., Canada; Med. Cand.

Glaucoma Clinic, University of Saskatchewan (Dr. Drance).; Department of Biochemistry, University of Saskatchewan (Dr. Woodford).

Footnotes
Submitted for publication April 21, 1960.

Anthranilic acid kindly supplied by the British Drug Houses, (Canada) Limited.

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