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Part I

BERNARD SCHWARTZ, M.D., Ph.D.

AMA Arch Ophthalmol. 1960;63(4):593-606.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The lens has long been recognized as an ideal experimental material for the study of the metabolism and permeability of an organ in vitro. Because of its avascularity and lack of nerve supply, as well as the fact that it is surrounded by a capsule and therefore can be easily removed and manipulated, the lens has been used increasingly in the past 10 years by many investigators. Particular interest has been centered on the technique of lens culture whereby the lens is studied in vitro for considerable periods of time up to several days.

It is the purpose of this paper to examine crtically the techniques of lens culture and to point out that a more physiological approach to the study of lens metabolism and permeability can be obtained by using a culture system based on the perfusion technique.

Review of Literature

One of the earliest attempts to use . . . [Full Text PDF of this Article]

Author Affiliations
Iowa City

From the Departments of Physiology and Ophthalmology, College of Medicine, State University of Iowa.

Footnotes
Submitted for publication Nov. 23, 1959.

Present address of author: Division of Ophthalmology, Department of Surgery, State University of New York, Downstate Medical Center, Brooklyn 3, N.Y.

Submitted in partial fulfilment of the requirements for the degree of Doctor of Philosophy in the Department of Physiology in the Graduate College of the State University of Iowa.

This study was supported in part by a Fight for Sight Award from the National Council to Combat Blindness Inc., New York and was carried out during the tenure of a Special Clinical Traineeship (BT-322) National Institute of Neurological Diseases and Blindness, United States Public Health Service.

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