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V. EVERETT KINSEY, Ph.D.; D. V. N. REDDY, Ph.D.; Isabel Aitken, B.S.; Ruth Carter, B.S.

AMA Arch Ophthalmol. 1959;62(1):78-83.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The rate of turnover of free carbon dioxide and bicarbonate ion (total carbon dioxide) in the anterior chamber of the eye of the rabbit has been estimated to be about 4% per minute.¹ The separate rates of turnover of the several components of the bicarbonate system were taken into account in making the calculation, but no allowance was made for the possible accelerating effect on the turnover due to the conversion of carbon dioxide to bicarbonate ion. Moreover, the calculated value for the rate also depended upon the validity of the assumption that the difference in the pH between the aqueous humor and plasma before and after giving acetazolamide (Diamox) remained constant, that the drug had no effect on the rate of diffusion of either carbon dioxide or bicarbonate ion, and that the flow rate of aqueous humor was reduced to one-half by the acetazolamide. Since these assumptions may . . . [Full Text PDF of this Article]

Footnotes
Submitted for publication Dec. 29, 1958.

The study was supported in part by Research Grant B-1100 from the National Institute of Neurological Diseases and Blindness, National Institutes of Health, U. S. Public Health Service, and Lederle Laboratories Division, American Cyanamid Company, Inc.

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