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Special Reference to the Infantile Form of the Disease

Y. MITSUI, M.D.; L. HANNA, M.A.; J. HANABUSA, M.D.; R. MINODA, M.D.; S. OGATA, M.D.; H. KURIHARA, M.D.; R. OKAMURA, M.D.; M. MIURA, B.S.

AMA Arch Ophthalmol. 1959;61(6):891-898.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Infection with adenovirus Type 8 appears to be regularly associated with clinical epidemic keratoconjunctivitis (EKC).^1-5 Jawetz et al.¹ isolated the prototype of this virus in 1955. Since that time, isolations of nine strains have been reported⁴ to June, 1957, eight from clinical EKC and one from an unidentified conjunctivitis which may have been an infantile form of EKC. Six of the nine strains were isolated from EKC in Japan, five by us and one by Tanaka.⁵

In the present study answers were sought to the following questions: 1. What is the best technique for isolation of adenovirus Type 8? 2. How often can it be isolated from clinical EKC? 3. How long after onset can it be isolated from active cases of EKC? 4. Is "infantile EKC" also regularly associated with infection by adenovirus Type 8? (The infantile form of EKC was first described by Mitsui . . . [Full Text PDF of this Article]

Author Affiliations
San Francisco

Department of Ophthalmology, Kumamoto University Medical School, Kumamoto, Japan (Dr. Mitsui, Dr. Hanabusa, Dr. Minoda, Dr. Ogata, Dr. Kurihara, Dr. Okamura, and Mr. Miura), and Department of Microbiology, University of California School of Medicine.

Footnotes
Submitted for publication Dec. 15, 1958.

This study was supported by grants from the Arnold Reuben Fight for Sight, National Council to Combat Blindness, Inc., New York, and the National Institutes of Health, Bethesda, Md. (B604).

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