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A Review of Fifty-Eight Cases

J. LAWTON SMITH, M.D.; DAVID G. COGAN, M.D.

AMA Arch Ophthalmol. 1959;61(5):687-694.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The syndrome of internuclear ophthalmoplegia is a characteristic disturbance of ocular motility which has considerable value in topical and etiologic diagnosis. It has been described a number of times, but we are not aware of a comprehensive study of the associated clinical findings or of a determination of the prognosis. Classification of the entity has also been somewhat obscured by varying terminology in the literature. The purpose of this report is to discuss briefly the nomenclature of this syndrome and to present the ophthalmologic and neurologic findings in a series of 58 cases of internuclear ophthalmoplegia.

Nomenclature

Lhermitte,¹ in 1922, is cited² as the first to use the term "ophthalmoplegia internuclearis." However, Leslie Paton,³ in 1921, had stated, "the dorsal longitudinal bundle is of such great clinical importance that I have ventured in the classification of ocular palsies to put in a separate class of 'internuclear palsies.' . . . [Full Text PDF of this Article]

Author Affiliations
Boston

Howe Laboratory of Ophthalmology, Harvard University Medical School.; Fellow in Ophthalmology (Dr. Smith), Special Traineeship BT-357, National Institute of Neurological Diseases and Blindness.

Footnotes
Submitted for publication Nov. 10, 1958.

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