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CHARLES I THOMAS, M.D.; MARY SUE BOVINGTON, B.S.; W. J. MacINTYRE, Ph.D.; HELEN HARRINGTON, Ph.D.; J. P. STORAASLI, M.D.

AMA Arch Ophthalmol. 1959;61(3):464-490.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

As our clinical investigations relating to uptake of radioactive phosphorus (P³²) by neoplastic and inflammatory lesions within the eye have proceeded during the past few years, it has become increasingly desirable to build a firmer foundation for these empirical clinical observations by means of controlled experiments in animals. In planning these experiments, the principal purpose has been to elucidate the clinical observations and to evaluate more accurately the various technical factors which enter into these determinations. Our investigations have been based on a large body of work and knowledge already gained by others on the uptake of radioactive material, particularly radioactive phosphorus, by various types of malignant tissue and on the facts that have been learned about the metabolism of phosphorus in normal and malignant cells. In addition, we could avail ourselves of a tested method of producing tumors in the eye, i. e., the technique of transplantation of . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland

Department of Surgery, Division of Ophthalmology, and Department of Radiology, Western Reserve University School of Medicine and University Hospitals.

Footnotes
Submitted for publication Aug. 28, 1958.

This research was supported in part by Research Grant B-188 (C4) of the Department of Health, Education, and Welfare, U. S. Public Health Service, National Institutes of Health, and performed in part under AEC Contract No. W-31-109-eng-78.

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