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  Vol. 61 No. 2, February 1959 TABLE OF CONTENTS
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Adenocarcinoma of the Meibomian Gland

A Pseudochalazion Entity

EDWARD C. SWEEBE, M.D.; DAVID G. COGAN, M.D.

AMA Arch Ophthalmol. 1959;61(2):282-290.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Although Baldauf described some tumors of the Meibomian gland in 1870, it was Allaire in 1891 who first identified an adenocarcinoma of the Meibomian gland. Since that time there have been approximately 120 Meibomian gland carcinomas reported in the literature (Bibliography). The Meibomian gland carcinomas comprise about 0.2% of all lid tumors (Welch and Duke). It appears that generalized metastases have occurred in 12 of these cases. The incidence of metastases may be even greater than this, as a good many cases had inadequate or no follow-up.

In their early stages, Meibomian gland carcinomas are frequently mistaken for chronic chalazia. The distinction between these two lid lesions becomes particularly important because these tumors do possess metastatic tendencies. Recently, we have had several cases in which the clinical diagnosis was "recurrent chalazion," but the pathologic specimen proved to be an adenocarcinoma of the Meibomian gland. We now have collected a total . . . [Full Text PDF of this Article]


Author Affiliations

Boston

Resident in Ophthalmology, Massachusetts Eye and Ear Infirmary (Dr. Sweebe). Professor of Ophthalmology, Harvard Medical School; Director, Howe Laboratory of Ophthalmology, Massachusetts Eye and Ear Infirmary, and surgeon at the Massachusetts Eye and Ear Infirmary (Dr. Cogan).


Footnotes

Submitted for publication July 21, 1958.

This investigation was supported in part by Traineeship Grant No. 2-B-5142(Ci) from the National Institute of Neurological Diseases and Blindness, U. S. Public Health Service.



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