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Advisability of a Combined Intraorbital and Intracranial Removal of the Affected Optic Nerve

ANATOLE DEKABAN, M.D.; GLENN DRAGER, M.D.

AMA Arch Ophthalmol. 1959;61(2):239-245.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Retinoblastoma is a highly malignant neoplasm which originates from the neuroectodermal elements of the retina. In a proportion of cases, the tumor is congenital and it may be detected during the early months of life by clinical means. However, the commonest time when definitive diagnosis is made is about 2 years of age. The incidence of retinoblastoma was estimated by Weller¹ as 1 in 34,000 births. The main principles of treatment consist of enucleation of the eye followed by radiation or radiotherapy alone. The true rate of complete recovery after institution of treatment is difficult to assess. In many of the published reports the authors do not follow their patients for a sufficient length of time to permit comprehensive evaluation.

We have attempted to review the literature published since 1945 of the documented cases of retinoblastoma that have been adequately followed. The criteria for accepting the reports required that . . . [Full Text PDF of this Article]

Author Affiliations
Bethesda, Md.

From the National Institute of Neurological Diseases and Blindness, National Institutes of Health, U. S. Public Health Service, Department of Health, Education, and Welfare.

Footnotes
Submitted for publication July 29, 1958.

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