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IV. Corneal Curvature

ALFRED J. COULOMBRE, Ph.D.; JANE L. COULOMBRE, B.S.

AMA Arch Ophthalmol. 1958;59(4):502-506.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

The cornea of the adult vertebrate eye has a smaller radius of curvature than the posterior segment of the eye. In very early development, by contrast, the radii of curvature of the cornea and sclera tend to be equal. The manner in which the corneal curvature develops, and the forces responsible for it, are the concern of this paper.

The interplay of a large number of factors is undoubtedly necessary for the normal development of the corneal bulge. The present effort, however, was confined to an investigation of the role of mechanical forces generated, on the one hand, by intraocular pressure and, on the other, by structural differentiation of the eye wall. Previous studies in this series^1,2 have demonstrated that these forces are responsible for the increase in size of the eye as a whole as well as for the normal expansion of the sclera, choroid coat, pigmented . . . [Full Text PDF of this Article]

Author Affiliations
New Haven, Conn.

Department of Anatomy, Yale University School of Medicine.

Footnotes
Received for publication Sept. 11, 1957.

This investigation was supported by a research grant, B-870 (C), from the Institute of Neurological Diseases and Blindness, Public Health Service.

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