 |
|
Growth of Lens Epithelium in CultureII. Effects of Oxygen Tension
J. G. MAMO, M.D.;
P. J. LEINFELDER, M.D.
AMA Arch Ophthalmol. 1958;59(3):420-422.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
The work of various investigators indicates that the lens consumes oxygen and that the amount of oxygen consumption differs in different portions of the lens. Ely (1949) has shown that the capsules and nuclei of both bovine and rabbit lenses have a negligible respiration, that the cortex and epithelium are the only parts that respire, with the epithelium probably playing the dominant role in the oxygen uptake. Kinsey and Frohman (1951) from their findings on the distribution of flavoprotein, cytochrome-cytochrome oxidase, and lactatepyruvate ratios in different portions of the lens have concluded that the epithelium appears to have a strictly aerobic type of metabolism, while the cortex and nucleus seem to have an anaerobic metabolism.
In order to investigate further the role played by the epithelium in the respiration of the lens, the effect of various oxygen tensions on cultures of growing human lens epithelium was studied.
Cultures of lens
. . . [Full Text PDF of this Article]
Author Affiliations
Philadelphia; Iowa City
From the Departments of Ophthalmology and Physiology, College of Medicine, The State University of Iowa.
Footnotes
Received for publication Aug. 7, 1957.
This work was supported in part by a special Clinical Traineeship (BT-274) from the National Institute of Neurological Diseases and Blindness, Public Health Service, and by a Grant for Study of Cell Metabolism (C-2371 M and G) from the National Institutes of Health.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
