This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

GUILLERMO PICÓ, M.D.

AMA Arch Ophthalmol. 1958;59(3):381-385.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Intraocular infection is perhaps the most dreaded of all the complications which may follow cataract extraction. When endophthalmitis is associated with a vitreous abscess, the chances of a successful end-result becomes very poor indeed. The introduction of modern chemotherapeutic and antibiotic agents has somewhat improved the outlook in these conditions in recent years, but intraocular infection has not yet become a complication to be viewed with equanimity.

Clinical and Experimental Observations

Between 1944 and 1948 occasional reports were published of the successful management of endophthalmitis by the sulfonamides and penicillin.^1-4 The successes, however, were few, and the outlook was not hopeful. The sulfonamides apparently penetrate the blood-aqueous barrier satisfactorily, but their narrow antibacterial spectrum limits their field of usefulness.

In 1944, von Sallmann and Meyer⁵ demonstrated that penicillin, even when given systemically in massive doses, does not penetrate sufficiently into the vitreous to produce concentrations adequate to control . . . [Full Text PDF of this Article]

Author Affiliations
Santurce, P. R.

From the Section of Ophthalmology, University of Puerto Rico School of Medicine.

Footnotes
Received for publication June 7, 1957.

Presented before the New Orleans Academy of Ophthalmology, New Orleans, Feb. 7, 1957.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?