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JED LEE HOWARD, A.B.; HENRY F. ALLEN, M.D.

AMA Arch Ophthalmol. 1958;59(1):68-72.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Herpetic infection of the eye constitutes one of the commoner and less responsive therapeutic problems faced by the ophthalmologist. The incidence and clinical features of this disease were catalogued by Gundersen¹ in his classic paper published more than 20 years ago. Thygeson, Kimura, and Hogan² have reviewed recent developments and have set forth the current status of the problem of herpes oculi. From these studies, it appears that herpes corneae may actually be increasing in frequency, that its complications are increasing in severity (partly as a result of injudicious treatment with corticosteroids), and that no specific chemotherapy exists for this disease.

The ecology of herpes simplex virus in human beings has been elucidated by Burnet³ and has been reviewed by Blank and Rake.⁴ Antibody surveys of various populations have shown a neutralization of herpes simplex by the sera of high percentages of persons. Uniformity of antiherpes . . . [Full Text PDF of this Article]

Author Affiliations
Boston

Howe Laboratory of Ophthalmology, Harvard University Medical School, Massachusetts Eye and Ear Infirmary.

Footnotes
Received for publication May 6, 1957.

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