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SYNG-MIN HONG, M.D.; PAUL A. CIBIS, M.D.; MARGUERITE CONSTANT, Ph.D.

AMA Arch Ophthalmol. 1957;58(5):632-640.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

In a previous study¹ evidence was produced that systemic administration of iodoacetic acid (IAA) and ionizing radiation, when administered to the eye only, elicit very similar ocular lesions. The clinical and histological changes produced by these two different agents in the lens and retina of rabbits correlate surprisingly well. However, there were some significant differences observed with regard to the latent periods of the exudative changes in the aqueous humor and vitreous (Table 1). The exudation appeared

somewhat earlier after irradiation than after IAA. The most puzzling feature, however, was presented by the fact that the leading cell type in the exudate of irradiated eyes consisted of polymorphonucleocytes, whereas the exudate in the eyes of IAA-treated animals was dominated by red blood cells. Such a difference in the exudative manifestations was difficult to understand and certainly was in contradiction to the commonly favored view that both IAA and . . . [Full Text PDF of this Article]

Author Affiliations
St. Louis

Footnotes
Received for publication April 16, 1957.

This research was supported in part by the U. S. A. F. under Contract AF 18 (600)-1269; monitored by the U. S. A. F. School of Aviation Medicine, Randolph Field, Texas.