This Article  • References  • Full text PDF  • Reply to article  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (14)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Experimental Study

JAMES E. McDONALD, M.D.

AMA Arch Ophthalmol. 1957;58(2):202-216.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Considerable confusion exists in the literature with regard to the events leading to the closure of a penetrating corneal wound, including both early and late changes. Among early components of wound healing are included those factors operative within the first hour after the penetrating wound. These include: (1) mechanical alterations in the cornea as a result of physical stress, (2) the role of fibrin, and (3) edema. Eliminated from consideration of early changes are appreciable effects of such components as epithelial proliferation, endothelial proliferation and regeneration of Descemet's membrane, and fibroblastic repair. Although there is a sizable body of literature on this subject of corneal wound healing, there is little effort to concentrate on what occurs in a corneal wound during the period immediately after the injury.

As regards the mechanical factor, there seems to be considerable disagreement as to what actually occurs. Parsons¹ stated, "the wound is rapidly . . . [Full Text PDF of this Article]

Author Affiliations
Oak Park, III.

From the Department of Ophthalmology, University of Illinois College of Medicine, Chicago.

Footnotes
Received for publication Jan. 25, 1957.

Presented at the Chicago Ophthalmological Society Meeting, Jan. 21, 1957.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?